Appraise effect modification and its impact on research.
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Effect ModificationIntroductionEffect modification, as used in research, describes a scenario where the extent of the effect of exposure variable on a given outcome variable varies according to a third variable. Thus, the absence or presence of an effect modifier alters the relationship of exposure with the outcome. With an example from health care or medical research, effect modification is the antagonism or synergy of an exposure depending on the ability of the effect modifier to decrease or increase a biological effect, respectively (Corraini et al., 2017). The significance of an effect modifier is its role in facilitating the identification of whether the outcome of exposure differs within study groups with varied characteristics. Hence effect modifier is relevant in determining homoge...
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