CRISPR/Cas9 -globin gene targeting in human haematopoietic stem cells
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Answer
SICKLE CELL ANEMIA IntroductionSickle cell anemia ranks among the most chronic diseases. The disease results from a recessive gene and patients normally inherit both defective copies from parents. Like many genetic diseases, the treatment is complicated and there exist none that can effectively rectify the defective genes. The best cure up until now has been bone marrow transplant. However, this comes with complications in the form of increased risks of infections among others. Recently, there have been high prospects of curing the disease through gene-editing technology. Breakthroughs in this field have resulted in Clustered Regularly Interspaced Palindromic Repeats (CRISPR) which seeks to rectify the genetic mutation that causes the disease. This paper analyzes sickle cell anemia before...
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