Blood Pressure Control
Instructions
Describe the physiology of blood pressure control. Causes of Primary Hypertension may include overactivity of the SNS; overactivity of the RAAS; alterations in other neurohumoral mediators of blood volume and vasomotor tone such as ANP, BNP, and adrenomedullin; inflammation; a complex interaction involving insulin resistance and endothelial function; and obesity-related hormonal changesa) Select 3 of the above potential causes and explain the pathophysiologic mechanisms of primary hypertension.b) Identify the organ damage that can occur as a result of Hypertension. Describe the pathophysiologic process of organ damage.c) Describe the pathophysiologic process that causes orthostatic hypotension.
Answer
Physiology of Blood Pressure Control The causes of primary hypertension include obesity relate changes, overactivity of the SNS, and inflammation. The pathophysiology of hypertension involves impairment of the renal pressure whereby the blood vessels become smaller and exerts a lot of pressure on the blood transporting tissues therefore, the heart is forced to work harder to maintain the pressure. It is estimated that 78 percent of obese people have hypertension and this is related to an increase in BMI. For the obese, the pathology of hypertension is linked to many mechanisms like malfunction of the kidney, SNS alteration, and hyperuricemia (De Meguel et al., 2015). The role of the SNS is to control the arterial pressure and any slight alteration of the SNS creates imbalances in the neur...
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