osteoporosis

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Etiology Osteoporosis is a metabolic disorder that affects the musculoskeletal system. The disorder develops as a result of an imbalance of bone resorption and bone formation. Under physiological conditions, a balance exists in bone formation (through osteoblast cells) and bone resorption (through osteoclasts).In osteoporosis, the osteoclastic activity is higher than the osteoblastic activity. The bone then becomes weak and brittle such that stress on the bone causes a fractureCommonly affected bones are the hip. Wrist, and spineHistory of osteoporosisIn 1822, Paton Cooper, a British anatomist noted an association between abnormal bones and fractures.In 1941, Fuller Albright most women had a risk of bone fracture after menopause. The disorder was known as osteoporosisMenopause results in l...

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